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The common everyday dose for the barbiturate addict is usually about one.5 grams. As tolerance to barbiturates develops, the quantity desired to keep up precisely the same degree of intoxication improves; tolerance into a deadly dosage, even so, isn't going to enhance a lot more than two-fold. As this occurs, the margin among an intoxicating dosage

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In scientific studies, secobarbital sodium and pentobarbital sodium have already been found to get rid of most of their performance for the two inducing and retaining rest by the tip of two months of continued drug administration at set doses. The shorter-, intermediate-, and, into a lesser degree, very long-performing barbiturates have been common

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